That which affects one’s welfare or happiness. A matter of interest to someone. The adposition before the matter of interest is usually over, about or for.
User Defined Definitions
"something that interests you because it is important or affects you"
"an anxious feeling"
"a feeling of sympathy for someone or something"
"something or someone that causes anxiety; a source of unhappiness"
"a commercial or industrial enterprise and the people who constitute it"